Ligase vs. Lyase

Ligasenoun

(enzyme) Any of a group of enzymes that catalyze the binding of two molecules; synthetase.

Ligasenoun

An enzyme which catalyzes creation of a covalent bond between two substrates, resulting in a larger product which is a combination of the two starting materials; especially, DNA ligase, an enzyme which creates a phosphate bond between 5´ and 3´ ends of a DNA chain, resulting in a longer chain of DNA. DNA ligase is important in normal biosynthesis of DNA in the replication cycle of cells.

Ligase

In biochemistry, a ligase is an enzyme that can catalyze the joining (ligation) of two large molecules by forming a new chemical bond. This is typically via hydrolysis of a small pendant chemical group on one of the larger molecules or the enzyme catalyzing the linking together of two compounds, e.g., enzymes that catalyze joining of C-O, C-S, C-N, etc.

Lyasenoun

(enzyme) Any of many classes of enzyme that catalyze the breaking of a specific form of bond

Lyasenoun

an enzyme which catalyses the joining of specified molecules or groups by a double bond.

Lyase

In biochemistry, a lyase is an enzyme that catalyzes the breaking (an reaction) of various chemical bonds by means other than hydrolysis (a reaction) and oxidation, often forming a new double bond or a new ring structure. The reverse reaction is also possible (called a ).