Pepsin vs. Renin

Pepsinnoun

(enzyme) A digestive enzyme that chemically digests, or breaks down, proteins into shorter chains of amino acids.

Pepsinnoun

A proteolytic enzyme (MW 34,500) contained in the secretory glands of the stomach. In the gastric juice it is united with dilute hydrochloric acid (0.2 per cent, approximately) and the two together constitute the active portion of the digestive fluid. It degrades proteins to proteoses and peptides, and is notable for having a very low pH optimum for its activity. It is the active agent in the gastric juice of all animals.

Pepsinnoun

an enzyme produced in the stomach that splits proteins into peptones

Pepsin

Pepsin is an endopeptidase that breaks down proteins into smaller peptides. It is produced in the gastric chief cells of the stomach lining and is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food.

Reninnoun

(enzyme) A circulating enzyme released by mammalian kidneys that converts angiotensinogen to angiotensin-I. Because its activity ultimately leads to formation of angiotensin-II and aldosterone, this hormone plays a role in maintaining blood pressure.

Reninnoun

a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure

Renin

Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular fluid (blood plasma, lymph and interstitial fluid) and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure.