Pepsin vs. Trypsin

Pepsinnoun

(enzyme) A digestive enzyme that chemically digests, or breaks down, proteins into shorter chains of amino acids.

Pepsinnoun

A proteolytic enzyme (MW 34,500) contained in the secretory glands of the stomach. In the gastric juice it is united with dilute hydrochloric acid (0.2 per cent, approximately) and the two together constitute the active portion of the digestive fluid. It degrades proteins to proteoses and peptides, and is notable for having a very low pH optimum for its activity. It is the active agent in the gastric juice of all animals.

Pepsinnoun

an enzyme produced in the stomach that splits proteins into peptones

Pepsin

Pepsin is an endopeptidase that breaks down proteins into smaller peptides. It is produced in the gastric chief cells of the stomach lining and is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food.

Trypsinnoun

(enzyme) A digestive enzyme that cleaves peptide bonds (a serine protease)

Trypsinnoun

A proteolytic enzyme present in the pancreatic juice. Unlike the pepsin of the gastric juice, it acts in a neutral or alkaline fluid, and not only converts the albuminous matter of the food into soluble peptones, but also, in part, into leucin and tyrosin.

Trypsinnoun

an enzyme of pancreatic origin; catalyzes the hydrolysis of proteins to smaller polypeptide units

Trypsin

Trypsin (EC 3.4.21.4) is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyzes proteins. Trypsin is formed in the small intestine when its proenzyme form, the trypsinogen produced by the pancreas, is activated.