Photoblinkingnoun
Alternating fluorescence and photobleaching
Photobleachingnoun
The destruction of a photochemical fluorescence by high-intensity light
Photobleaching
In optics, photobleaching (sometimes termed fading) is the photochemical alteration of a dye or a fluorophore molecule such that it permanently is unable to fluoresce. This is caused by cleaving of covalent bonds or non-specific reactions between the fluorophore and surrounding molecules.