Photoblinking vs. Photobleaching

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Photoblinkingnoun

Alternating fluorescence and photobleaching

Photobleachingnoun

The destruction of a photochemical fluorescence by high-intensity light

Photobleaching

In optics, photobleaching (sometimes termed fading) is the photochemical alteration of a dye or a fluorophore molecule such that it permanently is unable to fluoresce. This is caused by cleaving of covalent bonds or non-specific reactions between the fluorophore and surrounding molecules.

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